Posters from SPS2019 in Barcelona now live
As always we spend some good days at the SPS meeting, getting new acquaintances and meeting old friends and partners.
Steve Jenkinson (Pfizer, San Diego) did a well-received talk:
“The use of High-Throughput Multi Ion Channel profiling [on Qube 384 ed.] and in silico modelling in assessing arrhythmia risk: One Pharma’s experience and perspective”.
A very interesting presentation that addressed the Pfizer’s approach to early de-risking in cardiac safety. However, as an oral presentation, we cannot post it here, but watch out for similar talks in the future.
Five posters using QPatch was presented, emphasizing QPatch as the benchmark automated patch clamp solution for cardiac safety
“Electrophysiological characterization of human dopaminergic neurons derived from LUHMES cells”, Udo Kraushaar, Dominik Loser, Timm Danker, Clemens Möller, Marcel Leist. NMI (LINK)
“Functional Assessment of hNav1.x Ion Channels Using State- Dependent Protocols on the QPatch HT Automated Patch Clamp System”, Bryan Koci, Jennifer Wesley, Muthukrishnan Renganathan, Haiyang Wei, Diane Werth, Eurofins (LINK)
“Predicting Cardiac Proarrhythmic Risk Exclusively Using Automated Patch Clamp Data”, Edward SA Humphries, John Ridley, Robert Kirby and Marc Rogers, Metrion Biosciences, UK (LINK)
“Automatic estimation of hNaV1.5 channel inactivation improves pharmacological evaluation using the new adaptive protocol feature on Qube”, Anders Lindqvist, Sophion Biosciences (LINK)
“Activities for optimizing CiPA recommended protocols in patch clamp assays”, Katayama Y, Matsukawa H, Kanehisa T, Abe A, Yoshinaga T, Asakura K, Yoshikawa K, Tsurudome K, Tsukamoto T, Nissan Chemical, Japan Tobacco Inc., Eisai Co., Nippon Shinyaku, LSI Medience corp.and Sophion Bioscience (LINK)