Pharmacological evaluation of GABAA receptor subtypes on Qube 384

Studies of GABA_A ion channels using the automated patch clamp platform Qube 384 with focus on:

• Short ligand exposure with repetitive stimulations with EC₅₀
  concentrations of GABA
• Effects of agonists, antagonists and modulators
• Cumulative and non-cumulative concentration-response relationships
• Characterizing the pharmacological properties of four cell lines expressing different GABA_A subtypes