詳細
Verification of CiPA Recommended Voltage Protocols in Patch-Clamp Assay for hERG, Cav1.2 and Late Nav1.5 Currents
Year:
2019 First author:
Katayama et Al., 2019
詳細
Estimating hERG drug binding using temperature-controlled high throughput automated patch clamp
Year:
2018 First author:
Lindqvist et al. 2018
詳細
Are stem-cell cardiomyocytes a viable cellular reagent for automated patch-clamp?
Year:
2017 First author:
Morton
詳細
Temperature effect on hERG channel pharmacology measured using the Qube automated patch clamp system
Year:
2017 First author:
Lindqvist
詳細
Qube as a tool for assay optimization of CiPA cells and protocols by using multiple IC, EC solutions and hERG, Nav1.5 and Cav1.2 on the same QChip
Year:
2016 First author:
Schupp et al., 2016
詳細
Strategies for enhancing throughput in ion channel drug screening
Year:
2008 First author:
Jacobsen et al., 2008
詳細
Enhancing throughput with multiple cell lines per well
First author:
Olsen et al., 2006
詳細
Pharmacological characterization of voltage- and ligand-gated ion channels
Year:
2006 First author:
Olsen et al., 2006
詳細
Data quality is not affected by cell suspension density
Year:
2006 First author:
Mathes et al., 2006
詳細
“Clip Detecting” with series resistance compensation using an automated patch clamp system
Year:
2012 First author:
Løjkner et al., 2012
詳細
Characterization of hERG blockers using the automated QPatch 16 screening system
Year:
2005 First author:
Jacobsen et al., 2005
Papers
詳細
Characterization of Potassium Channel Modulators with QPatch™ Automated Patch-Clamp Technology: System Characteristics and Performance To cite this article:
Year:
2004 First author:
Kutchinsky et al., 2004
詳細
Synthesis and biological evaluation of novel 6,11-dihydro-5H-benzo[e]pyrimido- [5,4-b][1,4]diazepine derivatives as potential c-Met inhibitors
Year:
2017 First author:
Huang
詳細
MICE Models: Superior to the HERG Model in Predicting Torsade de Pointes
Year:
2013 First author:
Kramer et al., 2013
詳細
Automated Patch Clamping Using the QPatch
Year:
2009 First author:
Jones et al. 2009
詳細
Automated Planar Electrode Electrophysiology in Drug Discovery: Examples of the Use of QPatch in Basic Characterization and High Content Screening on Nav, KCa2.3, and Kv11.1 Channels
Year:
2009 First author:
Korsgaard et al., 2009
詳細
Discovery and electrophysiological characterization of SKF-32802; a novel hERG agonist found through a large-scale structural similarity search
Year:
2017 First author:
Donovan, Brian T. et Al.
詳細
QPatch: the missing link between HTS and ion channel drug discovery.
Year:
2009 First author:
Mathes
詳細
A new classifier-based strategy for in-silico ion-channel cardiac drug safety assessment
Year:
2015 First author:
Mistry et al., 2015
詳細
Screening system for drug-induced arrhythmogenic risk combining a patch clamp and heart simulator
Year:
2015 First author:
Okada et al., 2015
詳細
Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs
Year:
2017 First author:
Diness, J Goldin et Al
詳細
Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells: An In-Vitro Model to Predict Cardiac Effects of Drugs
Year:
2017 First author:
Sube
詳細
A dipolar cycloaddition reaction to access 6-methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridines enables the discovery synthesis and preclinical profiling of a P2X7 antagonist clinical candidate
Year:
2017 First author:
Chrovian et Al.
詳細
Biological Profiling of Coleoptericins and Coleoptericin-Like Antimicrobial Peptides from the Invasive Harlequin Ladybird Harmonia axyridis
Year:
2018 First author:
Hirsch et Al., 2018
詳細
Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel
Year:
2018 First author:
Haile et Al., 2018
Reports
詳細
QPatchにおけるCiPA Milnes hERG動態アッセイ
Year:
2018 First author:
Humphries et Al.
詳細
CHO-hERG DUO optimized for QPatch
Year:
2008 First author:
R Jacobsen
詳細
8 hours unattended hERG run with ≥97% success rate and consistent pharmacology results
Year:
2019 First author:
Schupp et Al., 2018
詳細
CHO-hERG Duo characterization and functional validation on QPatch
Year:
2011 First author:
Jacobsen et al., 2011
詳細
CHO-hERG Duo in multi-hole mode on QPatch
Year:
2011 First author:
Jacobsen et al., 2011
詳細
Stable response for ligand and voltage-gated ion channels on QPatch
Year:
2010 First author:
Olsen et al., 2010
詳細
Temperature control on Qube 384 – pharmacological dependency of hERG reference compounds
Year:
2017 First author:
R Jacobsen
KCaX.X
Posters
詳細
Wnt peptides control mammalian cancer cell membrane potential
Year:
2018 First author:
Ashmore et Al., 2018
Papers
詳細
Automated Planar Electrode Electrophysiology in Drug Discovery: Examples of the Use of QPatch in Basic Characterization and High Content Screening on Nav, KCa2.3, and Kv11.1 Channels
Year:
2009 First author:
Korsgaard et al., 2009
詳細
Development of a QPatch Automated Electrophysiology Assay for Identifying KCa3.1 Inhibitors and Activators
Year:
2013 First author:
Jenkins et al., 2013
詳細
NS19504: a novel BK channel activator with relaxing effect on bladder smooth muscle spontaneous phasic contractions
Year:
2014 First author:
Nausch, B
詳細
New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1
Year:
2014 First author:
Coleman et al., 2014
詳細
Inhibition of the potassium channel KCa3.1 by senicapoc reverses tactile allodynia in rats with peripheral nerve injury
Year:
2016 First author:
Staala et al., 2016
Reports
詳細
The intermediate conductance Ca2+ – activated K+ channel on Qube 384
Year:
2017 First author:
Sauter
詳細
HEK293-KCa on QPatch
Year:
2008 First author:
Jacobsen et al., 2008
KCNQ
Posters
詳細
Enhancing throughput with multiple cell lines per well
First author:
Olsen et al., 2006
詳細
Automation of patch clamp techniques: Technical validation through characterization of voltage-gated potassium channels and ligand-gated ion channels
Year:
2004 First author:
Krywkowski et al., 2004
Papers
詳細
Cell volume and membrane stretch independently control K+ channel activity
Year:
2009 First author:
Hammami et al., 2009
Kv1.1
Papers
詳細
Arrangement of Kv1 α subunits dictates sensitivity to tetraethylammonium
Year:
2010 First author:
Al-Sabi et Al
詳細
Porphyrin derivatives as potent and selective blockers of neuronal Kv1 channels
Year:
2014 First author:
Daly et al., 2014
Kv1.2
Papers
詳細
Arrangement of Kv1 α subunits dictates sensitivity to tetraethylammonium
Year:
2010 First author:
Al-Sabi et Al
詳細
Porphyrin derivatives as potent and selective blockers of neuronal Kv1 channels
Year:
2014 First author:
Daly et al., 2014
Kv1.3
Posters
詳細
Pharmacological characterization of voltage- and ligand-gated ion channels
Year:
2006 First author:
Olsen et al., 2006
Kv1.5
Posters
詳細
Enhancing throughput with multiple cell lines per well
First author:
Olsen et al., 2006
詳細
Pharmacological characterization of voltage- and ligand-gated ion channels
Year:
2006 First author:
Olsen et al., 2006
Simple and Effective Generation of Cell-based Assays for Ion Channels, Transporters, and Kinase Screening in Biologically Relevant Cells Using Scalable Transient Transfection
Year:
2014 First author:
Chen, Q
Papers
詳細
Isoindolinone compounds active as Kv1.5 blockers identified using a multicomponent reaction approach
Year:
2015 First author:
Kajanus et al.
Reports
詳細
CHO-Kv1.5 Voltage-gated potassium channels on QPatch
Year:
2009 First author:
Jensen et al., 2009
Kv2.1
Reports
詳細
Reliable Kv2.1 assasy and pharmacology on the QPatch
Year:
2017 First author:
Schupp et Al.
Kv3.X
Posters
詳細
Endogenous Ion Channels of Mammalian Cell Lines Characterization
Year:
2008 First author:
Friis et al., 2008
Papers
詳細
A Novel Modulator of Kv3 Potassium Channels Regulates the Firing of Parvalbumin-Positive Cortical Interneurons
Year:
2015 First author:
Rosata-Siri et al., 2015
詳細
Physiological modulators of Kv3.1 channels adjust firing patterns of auditory brainstem neurons
Year:
2016 First author:
Brown et al., 2016
Kv4.3
Papers
詳細
Screening system for drug-induced arrhythmogenic risk combining a patch clamp and heart simulator
Year:
2015 First author:
Okada et al., 2015
Ca2+ activated K-channels
Papers
詳細
Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs
Year:
2017 First author:
Diness, J Goldin et Al
詳細
Cell volume and membrane stretch independently control K+ channel activity
Year:
2009 First author:
Hammami et al., 2009
詳細
New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1
Year:
2014 First author:
Coleman et al., 2014
Reports
詳細
HEK293-KCa on QPatch
Year:
2008 First author:
Jacobsen et al., 2008
Kir
Reports
詳細
HEK-hKir2.1 on QPatch
Year:
2013 First author:
Olsen et al., 2013
