詳細
Verification of CiPA Recommended Voltage Protocols in Patch-Clamp Assay for hERG, Cav1.2 and Late Nav1.5 Currents
Year:
2019 First author:
Katayama et Al., 2019
詳細
Estimating hERG drug binding using temperature-controlled high throughput automated patch clamp
Year:
2018 First author:
Lindqvist et al. 2018
詳細
Are stem-cell cardiomyocytes a viable cellular reagent for automated patch-clamp?
Year:
2017 First author:
Morton
詳細
Temperature effect on hERG channel pharmacology measured using the Qube automated patch clamp system
Year:
2017 First author:
Lindqvist
詳細
Qube as a tool for assay optimization of CiPA cells and protocols by using multiple IC, EC solutions and hERG, Nav1.5 and Cav1.2 on the same QChip
Year:
2016 First author:
Schupp et al., 2016
詳細
Strategies for enhancing throughput in ion channel drug screening
Year:
2008 First author:
Jacobsen et al., 2008
詳細
Enhancing throughput with multiple cell lines per well
First author:
Olsen et al., 2006
詳細
Pharmacological characterization of voltage- and ligand-gated ion channels
Year:
2006 First author:
Olsen et al., 2006
詳細
Data quality is not affected by cell suspension density
Year:
2006 First author:
Mathes et al., 2006
詳細
“Clip Detecting” with series resistance compensation using an automated patch clamp system
Year:
2012 First author:
Løjkner et al., 2012
詳細
Characterization of hERG blockers using the automated QPatch 16 screening system
Year:
2005 First author:
Jacobsen et al., 2005
Papers
詳細
Characterization of Potassium Channel Modulators with QPatch™ Automated Patch-Clamp Technology: System Characteristics and Performance To cite this article:
Year:
2004 First author:
Kutchinsky et al., 2004
詳細
Synthesis and biological evaluation of novel 6,11-dihydro-5H-benzo[e]pyrimido- [5,4-b][1,4]diazepine derivatives as potential c-Met inhibitors
Year:
2017 First author:
Huang
詳細
MICE Models: Superior to the HERG Model in Predicting Torsade de Pointes
Year:
2013 First author:
Kramer et al., 2013
詳細
Automated Patch Clamping Using the QPatch
Year:
2009 First author:
Jones et al. 2009
詳細
Automated Planar Electrode Electrophysiology in Drug Discovery: Examples of the Use of QPatch in Basic Characterization and High Content Screening on Nav, KCa2.3, and Kv11.1 Channels
Year:
2009 First author:
Korsgaard et al., 2009
詳細
Discovery and electrophysiological characterization of SKF-32802; a novel hERG agonist found through a large-scale structural similarity search
Year:
2017 First author:
Donovan, Brian T. et Al.
詳細
QPatch: the missing link between HTS and ion channel drug discovery.
Year:
2009 First author:
Mathes
詳細
A new classifier-based strategy for in-silico ion-channel cardiac drug safety assessment
Year:
2015 First author:
Mistry et al., 2015
詳細
Screening system for drug-induced arrhythmogenic risk combining a patch clamp and heart simulator
Year:
2015 First author:
Okada et al., 2015
詳細
Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs
Year:
2017 First author:
Diness, J Goldin et Al
詳細
Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells: An In-Vitro Model to Predict Cardiac Effects of Drugs
Year:
2017 First author:
Sube
詳細
A dipolar cycloaddition reaction to access 6-methyl-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridines enables the discovery synthesis and preclinical profiling of a P2X7 antagonist clinical candidate
Year:
2017 First author:
Chrovian et Al.
詳細
Biological Profiling of Coleoptericins and Coleoptericin-Like Antimicrobial Peptides from the Invasive Harlequin Ladybird Harmonia axyridis
Year:
2018 First author:
Hirsch et Al., 2018
詳細
Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel
Year:
2018 First author:
Haile et Al., 2018
Reports
詳細
QPatchにおけるCiPA Milnes hERG動態アッセイ
Year:
2018 First author:
Humphries et Al.
詳細
CHO-hERG DUO optimized for QPatch
Year:
2008 First author:
R Jacobsen
詳細
8 hours unattended hERG run with ≥97% success rate and consistent pharmacology results
Year:
2019 First author:
Schupp et Al., 2018
詳細
CHO-hERG Duo characterization and functional validation on QPatch
Year:
2011 First author:
Jacobsen et al., 2011
詳細
CHO-hERG Duo in multi-hole mode on QPatch
Year:
2011 First author:
Jacobsen et al., 2011
詳細
Stable response for ligand and voltage-gated ion channels on QPatch
Year:
2010 First author:
Olsen et al., 2010
詳細
Temperature control on Qube 384 – pharmacological dependency of hERG reference compounds
Year:
2017 First author:
R Jacobsen
KCaX.X
Posters
詳細
Wnt peptides control mammalian cancer cell membrane potential
Year:
2018 First author:
Ashmore et Al., 2018
Papers
詳細
Automated Planar Electrode Electrophysiology in Drug Discovery: Examples of the Use of QPatch in Basic Characterization and High Content Screening on Nav, KCa2.3, and Kv11.1 Channels
Year:
2009 First author:
Korsgaard et al., 2009
詳細
Development of a QPatch Automated Electrophysiology Assay for Identifying KCa3.1 Inhibitors and Activators
Year:
2013 First author:
Jenkins et al., 2013
詳細
NS19504: a novel BK channel activator with relaxing effect on bladder smooth muscle spontaneous phasic contractions
Year:
2014 First author:
Nausch, B
詳細
New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1
Year:
2014 First author:
Coleman et al., 2014
詳細
Inhibition of the potassium channel KCa3.1 by senicapoc reverses tactile allodynia in rats with peripheral nerve injury
Year:
2016 First author:
Staala et al., 2016
Reports
詳細
The intermediate conductance Ca2+ – activated K+ channel on Qube 384
Year:
2017 First author:
Sauter
詳細
HEK293-KCa on QPatch
Year:
2008 First author:
Jacobsen et al., 2008
KCNQ
Posters
詳細
Enhancing throughput with multiple cell lines per well
First author:
Olsen et al., 2006
詳細
Automation of patch clamp techniques: Technical validation through characterization of voltage-gated potassium channels and ligand-gated ion channels
Year:
2004 First author:
Krywkowski et al., 2004
Papers
詳細
Cell volume and membrane stretch independently control K+ channel activity
Year:
2009 First author:
Hammami et al., 2009
Kv1.1
Papers
詳細
Arrangement of Kv1 α subunits dictates sensitivity to tetraethylammonium
Year:
2010 First author:
Al-Sabi et Al
詳細
Porphyrin derivatives as potent and selective blockers of neuronal Kv1 channels
Year:
2014 First author:
Daly et al., 2014
Kv1.2
Papers
詳細
Arrangement of Kv1 α subunits dictates sensitivity to tetraethylammonium
Year:
2010 First author:
Al-Sabi et Al
詳細
Porphyrin derivatives as potent and selective blockers of neuronal Kv1 channels
Year:
2014 First author:
Daly et al., 2014
Kv1.3
Posters
詳細
Pharmacological characterization of voltage- and ligand-gated ion channels
Year:
2006 First author:
Olsen et al., 2006
Kv1.5
Posters
詳細
Enhancing throughput with multiple cell lines per well
First author:
Olsen et al., 2006
詳細
Pharmacological characterization of voltage- and ligand-gated ion channels
Year:
2006 First author:
Olsen et al., 2006
Simple and Effective Generation of Cell-based Assays for Ion Channels, Transporters, and Kinase Screening in Biologically Relevant Cells Using Scalable Transient Transfection
Year:
2014 First author:
Chen, Q
Papers
詳細
Isoindolinone compounds active as Kv1.5 blockers identified using a multicomponent reaction approach
Year:
2015 First author:
Kajanus et al.
Reports
詳細
CHO-Kv1.5 Voltage-gated potassium channels on QPatch
Year:
2009 First author:
Jensen et al., 2009
Kv2.1
Reports
詳細
Reliable Kv2.1 assasy and pharmacology on the QPatch
Year:
2017 First author:
Schupp et Al.
Kv3.X
Posters
詳細
Endogenous Ion Channels of Mammalian Cell Lines Characterization
Year:
2008 First author:
Friis et al., 2008
Papers
詳細
A Novel Modulator of Kv3 Potassium Channels Regulates the Firing of Parvalbumin-Positive Cortical Interneurons
Year:
2015 First author:
Rosata-Siri et al., 2015
詳細
Physiological modulators of Kv3.1 channels adjust firing patterns of auditory brainstem neurons
Year:
2016 First author:
Brown et al., 2016
Kv4.3
Papers
詳細
Screening system for drug-induced arrhythmogenic risk combining a patch clamp and heart simulator
Year:
2015 First author:
Okada et al., 2015
Ca2+ activated K-channels
Papers
詳細
Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs
Year:
2017 First author:
Diness, J Goldin et Al
詳細
Cell volume and membrane stretch independently control K+ channel activity
Year:
2009 First author:
Hammami et al., 2009
詳細
New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1
Year:
2014 First author:
Coleman et al., 2014
Reports
詳細
HEK293-KCa on QPatch
Year:
2008 First author:
Jacobsen et al., 2008
Kir
Reports
詳細
HEK-hKir2.1 on QPatch
Year:
2013 First author:
Olsen et al., 2013
お問い合わせ
製品
QPatchQube 384
#mc_embed_signup{background:#fff; clear:left; font:14px Helvetica,Arial,sans-serif; }
/* Add your own MailChimp form style overrides in your site stylesheet or in this style block.
We recommend moving this block and the preceding CSS link to the HEAD of your HTML file. */
Subscribe to our newsletter
* indicates required
(function($) {window.fnames = new Array(); window.ftypes = new Array();fnames[0]='EMAIL';ftypes[0]='email';fnames[1]='FNAME';ftypes[1]='text';fnames[2]='LNAME';ftypes[2]='text';}(jQuery));var $mcj = jQuery.noConflict(true);
This page is not optimized for smartphones and tablets.
