Programme
Day 1 – Wednesday
08.00 Registration and tea/coffee
09.00 Welcome remarks
Session 1 – Professor Martin Gosling, Sussex University
09.05 Dr Marc Estacion – Yale University
Precision medicine targeting pain: progress finding treatments for specific Nav1.7 mutations
09.30 Professor Guiseppe Lauria – Fondazione IRCCS Istituto Neurologico “Carlo Besta”, Milan
Sodium-channel related painful neuropathies
09.55 Professor Stephen Tucker – University of Oxford
New Insights into the Mechanisms of K2P Channel Gating
10.20 Tea/coffee – exhibits and poster
11.40 Professor Junko Kurokawa – Pharmaceutical School of University of Shizuoka
Local control of sex hormonal signaling regulation in cardiac ion channels
11.40 Professor David Wyllie – Edinburgh University
The altered structure-function relationship of dendritic spines in a model of fragile X syndrome
12.05 Professor Mike Edwardson – University of Cambridge
Visualizing activation-induced structural changes in ionotropic glutamate receptors using fast-scan AFM
12.30 Lunch
Session 2 – Dr Howard Baylis, University of Cambridge
14.00 Professor Trevor Smart – University College London (UCL)
TBA
14.25 Professor Shigetoshi Oiki – University of Fukui
Ion permeation and gating of the KcsA potassium channel reconstituted in the manipulated membrane
14.50 Professor David Beeson – University of Oxford
Genetic disorders of the neuromuscular synapse. How can we treat them?
15.15 Tea/coffee – exhibits and poster
16.00 Dr Anthony Lewis – University of Portsmouth
Biophysics and regulation of potassium channels from pathogenic fungi
16.25 Dr Paul Miller – University of Oxford
Observing modulation of a GABA-A receptor
16.50 Professor Gong Chen – Pennsylvania State University
In Vivo cell conversion for brain repair: reversing glial scar back to neural tissue
17.15 Wrap up
19.00 Dinner in the Great Hall of Clare College
Day 2 – Thursday
08.00 Tea/coffee
09.00 Welcome remarks
Session 3 – Professor Derek Bowie, McGill University
09.15 Dr Neil Castle – Icagen
Targeting Nav1.9 for Development of New Pain Therapies
09.40 Dr Ivan Kadurin – University College London (UCL)
Post-translational regulation of Cav channels via auxiliary subunits
10.05 Professor Andrew Tinker – Barts and the London School of Medicine and Dentistry
The role of ATP-sensitive K+ channels in the cardiovascular system
10.20 Tea/coffee – exhibits and poster
11.20 Dr Norio Hashimoto – Nissan Chemical Industries, Ltd.
Targeting T-type calcium channel for anti-pain drug discovery
11.45 Dr Jamel Mankouri – University of Leeds
Cellular ion channels as new anti-viral targets
12.10 Professor Alistair Mathie – University of Kent
Two pore domain potassium channels as therapeutic targets
12.35 Lunch
Session 4 – Professor Mustafa Djamgoz
14.00 Professor Dr Luis Pardo – Max-Plank Institut, Göttingen
Kv10.1 and the cell cycle: A two-way road
14.25 Dr William Brackenbury – University of York
Targeting breast cancer invasion and metastasis with antiepileptic drugs
14.50 Professor Annarosa Archangeli – University of Florence
hERG Channels: From anti-targets to novel targets for cancer therapy
15.15 Dr Aneesh Karatt-Vellatt – Iontas Ltd
KnotBodies: Ion channel blocking antibodies by fusing Knottins into peripheral CDR loops
15.40 Wrap up